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HRID390942

反应详情

EQUATION

反应方程式

HRID 390942 的结构方程式

REACTANTS

反应物

2
结构：COc1ncc(B(O)O)cn1
HCID2736778

2-Methoxypyrimidine-5-boronic acid

C5H7BN2O3

结构：CS(=O)(=O)N1CCN(Cc2cc3nc(Cl)nc(N4CCOCC4)c3o2)CC1
HCID56833744

未命名化合物

PRODUCTS

生成物

1
结构：COc1ncc(-c2nc(N3CCOCC3)c3oc(CN4CCN(S(C)(=O)=O)CC4)cc3n2)cn1
HCID58233957

未命名化合物

PROCEDURE

实验过程

2-Chloro-6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-morpholinofuro[3,2-d]pyrimidine (Example 153) was reacted with 2-methoxypyrimidine-5-boronic acid via General Procedure E to give, after purification by reverse HPLC, 4 mg of 237. MS (Q1) 490 (M+).

WORKUP

后处理

  1. customto give
  2. customafter purification by reverse HPLC, 4 mg of 237