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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 390986Generated: October 28, 2026

Hydrochloric Acid → HCID 43810645, compound

https://huagongshe.com/reaction/390986

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 46180234HCID 46180234—
SolventMethanolHCID 887—
SolventDiethyl EtherHCID 3283—
SolventDichloromethaneHCID 6344—
ProductHCID 43810645HCID 43810645—

Reaction Steps

4-(3-Fluoro-benzenesulfonyl)-piperazine-1-carboxylic acid tert-butyl ester (919 mg) was dissolved in methanol (10 ml) and dichloromethane (5 ml), 2M HCl in diethyl ether (12 ml) was added and the reaction mixture was stirred at room temperature overnight. Volatiles were removed in vacuo to yield 4-(3-fluoro-benzenesulfonyl)-piperazine hydrochloride salt (807 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08383620B2
Source datasetuspto-grants-2013_02
ORD IDord-5fc72b68a0b1475c90522c02cba78b30
Source noteuspto-grants-2013_02