HRID391073

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC1(C)OB(c2cnc(N)c([N+](=O)[O-])c2)OC1(C)C

HCID46738009

3-Nitro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine

C11H16BN3O4

结构：CS(=O)(=O)N1CCN(Cc2cc3c(N4CCOCC4)nc(Cl)nc3s2)CC1

HCID56833946

未命名化合物

PRODUCTS

生成物

结构：CS(=O)(=O)N1CCN(Cc2cc3c(N4CCOCC4)nc(-c4cnc(N)c([N+](=O)[O-])c4)nc3s2)CC1

HCID58234068

未命名化合物

收率 16.8%

PROCEDURE

实验过程

4-(2-Chloro-6-((4-(methylsulfonyl)piperazin-1-yl)methyl)thieno[2,3-d]pyrimidin-4-yl)morpholine (100 mg, 0.2 mmol) was reacted with 3-nitro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine (0.24 g, 0.9 mmol) according to General Procedure Suzuki to afford 360 (18 mg) following reverse phase HPLC purification. MS (Q1) 535 (M)+