Pyridine → HCID 67016587, compound

Participants

Reaction Conditions

Reaction Steps

Synthesis method: 2,2-bis(trifluoromethyl)benzidine was dissolved in tetrahydrofuran followed by the addition of maleic anhydride and allowing to react for 30 minutes while heating at 60° C. Subsequently, pyridine and acetic anhydride were added followed by additionally reacting for 1 hour. The solvent was removed from the resulting reaction solution with an evaporator and the resulting solid was recrystallized with acetic anhydride to obtain a pure product of 2-trifluoromethyl-4-maleimidophenyl biphenyl.

Provenance & Evidence