Methyl iodide → Quinoline methiodide

HRID 391163Notes

Reaction equation

HRID 391163 reaction equation
[N:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1.[CH3:11][I:12]>O1CCOCC1>[I-:12].[CH3:11][N+:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 7047Quinoline

Product 1

HCID 19848Quinoline methiodide

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Conditions

Temperature
150 °C

Procedure

N-methylquinolinium iodide (Compound III) was synthesized according to the description in the aforementioned reference. Specifically, 2.4 mL of quinoline and 4 mL of methyl iodide were added to 42 mL of anhydrous dioxane, which was stirred at 150° C. for one hour. Thereafter, it was filtered and thereby a precipitate was collected and then washed with ether and petroleum ether. This was dried and thus N-methylquinolinium iodide (Compound III) was obtained.

Workup

  1. customN-methylquinolinium iodide (Compound III) was synthesized
  2. filtrationThereafter, it was filtered
  3. customa precipitate was collected
  4. washwashed with ether and petroleum ether
  5. customThis was dried

Sources & evidence

ORD record
ord-6af5ef6efe2a4092938a0c01e49a2c54
Source dataset
uspto-grants-2013_02
Patent number
US08383792B2

Reaction notes

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