反应详情

3.56 Parts of 2-amino-4-chloro-6-chloromethylpyrimidine was dissolved in 53 parts of dry diethyl ether and dry hydrogen chloride was bubbled through the solution, with stirring, until no further solid precipitated the solid was filtered, washed with ether and dried in vacuo. Recrystallisation from acetone gave 2-amino-4-chloro-6-chloromethyl-pyrimidine hydrochloride m.p. 145°-150° C. (decomposition).

1. customwas bubbled through the solution
2. customprecipitated the solid
3. filtrationwas filtered
4. washwashed with ether
5. customdried in vacuo
6. customRecrystallisation from acetone