Benzoyl chloride, 3-bromo- → HCID 25054619, compound

HRID 391502Notes

Reaction equation

HRID 391502 reaction equation
N1N[N:3]=[N:4][C:5]=1[C:6]1[CH:7]=[N:8][CH:9]=[CH:10][CH:11]=1.[Br:12][C:13]1[CH:14]=[C:15]([CH:19]=[CH:20][CH:21]=1)[C:16](Cl)=[O:17]>CC1C=CC=CC=1C>[Br:12][C:13]1[CH:14]=[C:15]([C:16]2[O:17][C:5]([C:6]3[CH:7]=[N:8][CH:9]=[CH:10][CH:11]=3)=[N:4][N:3]=2)[CH:19]=[CH:20][CH:21]=1

Participants

4

Reactant 2

HCID 74377Benzoyl chloride, 3-bromo-HCID 1510915-(3-Pyridyl)tetrazole

Product 1

HCID 25054619HCID 25054619, compound

Reagents, catalysts & solvents 1

HCID 7237O-XyleneSolvent

Procedure

16.8 g (114 mmol) of 3-(2H-tetrazol-5-yl)pyridine) according to Synthesis Example 7 and 25 g (114 mmol) of 3-bromobenzoylchloride were dissolved in 180 mL of o-xylene. The solution was reacted at 150° C. for 8 hours. The acquired reactant was purified under reduced pressure and washed with methanol, obtaining 30 g (Y=87%) of a white solid.

Workup

  1. customThe solution was reacted at 150° C. for 8 hours
  2. customThe acquired reactant was purified under reduced pressure
  3. washwashed with methanol
  4. customobtaining 30 g (Y=87%) of a white solid

Sources & evidence

ORD record
ord-69451d115958415b9c722df003378e15
Source dataset
uspto-grants-2013_02
Patent number
US08383932B2

Reaction notes

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