反应详情

A solution of 1-(4′-methoxycarbonylphenyl)imidazole (153 g, 0.76 mol) in 1:1 THF/methanol (600 ml) is admixed with methyl iodide (196 ml, 2.27 mol) and stirred at room temperature under argon for 16 h. After concentration of the solution, the precipitated product is filtered off and washed with THF. Yield: 59%.

1. filtrationAfter concentration of the solution, the precipitated product is filtered off
2. washwashed with THF