HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → HCID 178498104, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | Methyl 4-(1H-imidazol-1-yl)benzoate | HCID 2766374 | — |
| Solvent | MeOH tetrahydrofuran | HCID 21899815 | — |
| Product | HCID 178498104 | HCID 178498104 | 59% |
Reaction Steps
A solution of 1-(4′-methoxycarbonylphenyl)imidazole (153 g, 0.76 mol) in 1:1 THF/methanol (600 ml) is admixed with methyl iodide (196 ml, 2.27 mol) and stirred at room temperature under argon for 16 h. After concentration of the solution, the precipitated product is filtered off and washed with THF. Yield: 59%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08384068B2 |
| Source dataset | uspto-grants-2013_02 |
| ORD ID | ord-21e057ffbeb843aba9ac696796e5e7ab |
| Source note | uspto-grants-2013_02 |