Sulfuric Acid → HCID 86639893, compound

Participants

Reaction Steps

10.65 g of N-methylglutamic acid was placed in a 250 ml round-bottom flask, and 100 ml of water was added to the flask and stirred by using a magnetic stirrer for 30 minutes. Then, 6.38 g of concentrated sulfuric acid (concentration: 98%) was slowly dropped into the flask under stirring, and stirred for additional 2 hours after dropping. After the reaction, the reaction solution was concentrated, azeotroped with toluene to further remove the water and dried under vacuum to obtain 16.5 g of N-methylglutamic acid sulfate as yellow oil (Yield: 97.7%).

Provenance & Evidence