HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Cyanide → 3-(7-Methoxybenzofuran-3-yl)-propionitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Cyanide | HCID 8929 | — |
| Reactant | 3-(2-Bromoethyl)-7-methoxybenzofuran | HCID 22662937 | — |
| Product | 3-(7-Methoxybenzofuran-3-yl)-propionitrile | HCID 22662953 | 97.2% |
Reaction Steps
This compound was prepared by the same method as for intermediate 27, using 2.87 g (11.25 mmol) of 3-(2-bromoethyl)-7-methoxybenzofuran and 1.1 g (22.5 mmol) of sodium cyanide, to afford 2.2 g (97%) of the title compound: MS (ESI) m/z 201 [M]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06800637B2 |
| Source dataset | uspto-grants-2004_10 |
| ORD ID | ord-4e9a2ac44dad4b1eac666cc11dea3c56 |
| Source note | uspto-grants-2004_10 |