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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 392168Generated: October 30, 2026

Cyclopropylamine hydrochloride → 2-Cyclopropylamino-6,7-dimethoxy-4-(3-nitrophenyl)quinazoline

https://huagongshe.com/reaction/392168

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclopropylamine hydrochlorideHCID 11708049—
Reactant2-Chloro-6,7-dimethoxy-4-(3-nitrophenyl)quinazolineHCID 12150398—
Product2-Cyclopropylamino-6,7-dimethoxy-4-(3-nitrophenyl)quinazolineHCID 1215040325.3%

Reaction Steps

Starting from 500 mg 2-chloro-6,7-dimethoxy-4-(3-nitrophenyl)quinazoline and 414 mg cyclopropylamine hydrochloride, 134 mg of the title compound was obtained in the same manner as in Production Example 4.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06800644B2
Source datasetuspto-grants-2004_10
ORD IDord-9266999a06704d8c817963b96dae6414
Source noteuspto-grants-2004_10