HuagongsheHuagongshe Chemistry Print Report · For research reference only
Guaiacol → N-(3-(2-Methoxyphenoxy)phenyl) pyrid-3-ylmethylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Guaiacol | HCID 460 | — |
| Reactant | 3-Bromo-N-(pyridin-3-ylmethyl)aniline | HCID 22663898 | — |
| Product | N-(3-(2-Methoxyphenoxy)phenyl) pyrid-3-ylmethylamine | HCID 22663896 | — |
Reaction Steps
Using the method of Example 342 using N-(3-bromophenyl)pyridin-3-ylmethylamine and guaiacol (Aldrich) and purifying via preparative HPLC eluting with 1:1 DCM/ethyl acetate gave N-(3-(2-Methoxyphenoxy)phenyl) pyrid-3-ylmethylamine. Anal Calcd for C19H18N2O2.0.5H2O: C, 72.36; H, 6.07; N, 8.88. Found: C, 72.43; H, 5.80; N, 8.96. MS found 307.2 [M+H]+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06800651B2 |
| Source dataset | uspto-grants-2004_10 |
| ORD ID | ord-14664bfda2b44c47ba90ad802b07d5d8 |
| Source note | uspto-grants-2004_10 |