huagongshe.com
HRID392412

反应详情

EQUATION

反应方程式

HRID 392412 的结构方程式

REACTANTS

反应物

2
结构：CCS(=O)(=O)Cl
HCID11667

Ethanesulfonyl chloride

C2H5ClO2S

结构：COc1ccccc1Oc1cccc(NCc2cccnc2)c1
HCID22663896

未命名化合物

PRODUCTS

生成物

1
结构：CCS(=O)(=O)N(Cc1cccnc1)c1cccc(Oc2ccccc2OC)c1
HCID10294298

N-[3-(2-Methoxyphenoxy)phenyl]-N-(3-pyridinylmethyl)ethanesulfonamide

C21H22N2O4S

PROCEDURE

实验过程

Using the method of Example 342 using N-(3-(2-methoxyphenoxy)phenyl)pyridin-3-ylmethylamine and ethanesulfonyl chloride (Aldrich) and purifying via preparative HPLC eluting with 98:2 to 96:4 DCM/MeOH gave the title compound. Anal Calcd for C21H22N2O4S: C, 63.30; H, 5.56; N, 7.03. Found: C, 63.16; H, 5.51; N, 6.64. MS found 398.9 [M+H]+

WORKUP

后处理

  1. custompurifying via preparative HPLC
  2. washeluting with 98:2 to 96:4 DCM/MeOH