2,2,2-Trifluoroethanol → HCID 11078236, compound

HRID 392705Notes

Reaction equation

[C:1]1([CH:7]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[C:8]([N:10]=[C:11]=[O:12])=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[F:19][C:20]([F:24])([F:23])[CH2:21][OH:22]>>[F:19][C:20]([F:24])([F:23])[CH2:21][O:22][C:11](=[O:12])[NH:10][C:8](=[O:9])[CH:7]([C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1)[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

Participants

Reactant 2

HCID 64092,2,2-Trifluoroethanol

HCID 11264874Diphenylacetyl isocyanate

Product 1

HCID 11078236HCID 11078236, compound

Procedure

The title compound, white solid, m.p.=125-127° C. and MS: m/e=337.3 (M+H+) was prepared in accordance with the general method of example 1 from diphenylacetyl isocyanate and 2,2,2 trifluoro-ethanol.

Sources & evidence

ORD record: ord-e5f9cba0b94d4ffcbd89a4e7a63e68ab
Source dataset: uspto-grants-2004_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06803381B1

Reaction notes

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