2,2,2-Trifluoroethanol → HCID 69921273, compound

HRID 392711Notes

Reaction equation

HRID 392711 reaction equation
[C:1]1([C:7]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)([CH3:13])[C:8]([N:10]=[C:11]=[O:12])=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[F:20][C:21]([F:25])([F:24])[CH2:22][OH:23]>>[F:20][C:21]([F:25])([F:24])[CH2:22][O:23][C:11](=[O:12])[NH:10][C:8](=[O:9])[C:7]([C:1]1[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1)([C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)[CH3:13]

Participants

3

Reactant 2

HCID 64092,2,2-TrifluoroethanolHCID 22661083HCID 22661083, compound

Product 1

HCID 69921273HCID 69921273, compound

Procedure

The title compound, white solid, m.p.=143-145° C., MS: m/e=351.3 (M+H+) was prepared in accordance with the general method of example 1 from 2,2-diphenylpropionyl isocyanate and 2,2,2-trifluoro-ethanol.

Sources & evidence

ORD record
ord-96282e45e6124955bd0dce770a526aad
Source dataset
uspto-grants-2004_10
Patent number
US06803381B1

Reaction notes

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