2,2-Diphenylacetyl chloride → N-[1,3,4]Oxadiazol-2-yl-2,2-diphenyl-acetamide
Reaction equation
[O:1]1[CH:5]=[N:4][N:3]=[C:2]1[NH2:6].[C:7]1([CH:13]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[C:14](Cl)=[O:15])[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1>>[O:1]1[CH:5]=[N:4][N:3]=[C:2]1[NH:6][C:14](=[O:15])[CH:13]([C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1Participants
3
Procedure
The title compound, light yellow solid, m.p. 131-132° C. and MS: m/e=279.2 (M+) was prepared in accordance with the general method of example 44a from [1,3,4]oxadiazol-2-ylamine and 2,2-diphenylacetic acid chloride.
Sources & evidence
- ORD record
- ord-09034b4a402c444b857b37db8b2601c3
- Source dataset
- uspto-grants-2004_10
- Patent number
- US06803381B1
Reaction notes
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