2,2-Diphenylacetyl chloride → N-(5-(2-methoxyethyl)-1,3,4-oxadiazol-2-yl)-2,2-diphenylacetamide

HRID 392731Notes

Reaction equation

HRID 392731 reaction equation
[C:1]1([CH:7]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[C:8](Cl)=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:17][O:18][CH2:19][CH2:20][C:21]1[O:25][C:24]([NH2:26])=[N:23][N:22]=1>>[CH3:17][O:18][CH2:19][CH2:20][C:21]1[O:25][C:24]([NH:26][C:8](=[O:9])[CH:7]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[C:1]2[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=2)=[N:23][N:22]=1

Participants

3

Reactant 2

HCID 746372,2-Diphenylacetyl chlorideHCID 226610755-(2-Methoxyethyl)-1,3,4-oxadiazol-2-amine

Product 1

HCID 9840749N-(5-(2-methoxyethyl)-1,3,4-oxadiazol-2-yl)-2,2-diphenylacetamide

Procedure

The title compound, white solid, m.p. 114-115° C. and MS: m/e=338.2 (M+H+) was prepared in accordance with the general method of example 44a from 2,2-diphenylacetic acid chloride and [5-(2-methoxy-ethyl)-[1,3,4]oxadiazol-2-yl]-amine.

Sources & evidence

ORD record
ord-3200e435402b47eaa0df0785efe068b6
Source dataset
uspto-grants-2004_10
Patent number
US06803381B1

Reaction notes

Loading…