2,2-Diphenylacetyl chloride → N-(5-Ethyl-oxazol-2-yl)-2,2-diphenyl-acetamide

HRID 392738Notes

Reaction equation

HRID 392738 reaction equation
[CH2:1]([C:3]1[O:7][C:6]([NH2:8])=[N:5][CH:4]=1)[CH3:2].[C:9]1([CH:15]([C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[C:16](Cl)=[O:17])[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1>>[CH2:1]([C:3]1[O:7][C:6]([NH:8][C:16](=[O:17])[CH:15]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)=[N:5][CH:4]=1)[CH3:2]

Participants

3

Reactant 2

HCID 746372,2-Diphenylacetyl chlorideHCID 226610805-Ethyl-2-oxazolamine

Product 1

HCID 9796553N-(5-Ethyl-oxazol-2-yl)-2,2-diphenyl-acetamide

Procedure

The title compound, white solid, m.p. 148-149° C. and MS: m/e=307.3 (M+H+) was prepared in accordance with the general method of example 44a from 5-ethyl-oxazol-2-ylamine and 2,2-diphenylacetic acid chloride.

Sources & evidence

ORD record
ord-bae7bcf1f1914c8fa7f6a416f442124e
Source dataset
uspto-grants-2004_10
Patent number
US06803381B1

Reaction notes

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