2,2-Diphenylacetyl chloride → N-(5-Methyl-oxazol-2-yl)-2,2-diphenyl-acetamide

HRID 392740Notes

Reaction equation

HRID 392740 reaction equation
[CH3:1][C:2]1[O:6][C:5]([NH2:7])=[N:4][CH:3]=1.[C:8]1([CH:14]([C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[C:15](Cl)=[O:16])[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1>>[CH3:1][C:2]1[O:6][C:5]([NH:7][C:15](=[O:16])[CH:14]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)=[N:4][CH:3]=1

Participants

3

Reactant 2

HCID 746372,2-Diphenylacetyl chlorideHCID 124951335-Methyl-1,3-oxazol-2-amine

Product 1

HCID 9839009N-(5-Methyl-oxazol-2-yl)-2,2-diphenyl-acetamide

Procedure

The title compound, off-white solid, m.p. 166-168° C. and MS: m/e=292.2 (M+) was prepared in accordance with the general method of example 44a from 5-methyl-oxazol-2-ylamine and 2,2-diphenylacetic acid chloride.

Sources & evidence

ORD record
ord-040205c5ea1748e99a5b5e6c4321ff43
Source dataset
uspto-grants-2004_10
Patent number
US06803381B1

Reaction notes

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