2,2-Diphenylacetyl chloride → HCID 9797098, compound

HRID 392745Notes

Reaction equation

HRID 392745 reaction equation
[CH:1]1([C:4]2[N:8]=[C:7]([NH2:9])[O:6][N:5]=2)[CH2:3][CH2:2]1.[C:10]1([CH:16]([C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)[C:17](Cl)=[O:18])[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1>>[CH:1]1([C:4]2[N:8]=[C:7]([NH:9][C:17](=[O:18])[CH:16]([C:10]3[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=3)[C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=3)[O:6][N:5]=2)[CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 746372,2-Diphenylacetyl chlorideHCID 226610563-Cyclopropyl-1,2,4-oxadiazol-5-amine

Product 1

HCID 9797098HCID 9797098, compound

Procedure

The title compound, white solid, m.p. 163° C. and MS: m/e=219 (M+) was prepared in accordance with the general method of example 44a from 3-cyclopropyl-[1,2,4]oxadiazol-5-ylamine (Helv. Chim. Acta, 49(1966), 1430-1432) and 2,2-diphenylacetic acid chloride.

Sources & evidence

ORD record
ord-2a6736ecef7d4942aad04c1bec54ca87
Source dataset
uspto-grants-2004_10
Patent number
US06803381B1

Reaction notes

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