反应详情

To a solution of O-(2-Hydroxyethyl)resorcinol (4 g) and sodium hydroxide (1.04 g) dissolved in methanol (60 mL) was added benzyl bromide (4.44 g), and the resulting reaction mixture was stirred overnight. After this time, approximately 30 mL of the methanol was removed in vacuo, and the mixture was diluted with methylene chloride (100 mL). The organics were washed with water and aqueous 1N NaOH, dried, and concentrated to provide 2-(3-benzyloxyphenoxy)ethanol (5.03 g).

1. customthe resulting reaction mixture
2. customAfter this time, approximately 30 mL of the methanol was removed in vacuo
3. additionthe mixture was diluted with methylene chloride (100 mL)
4. washThe organics were washed with water and aqueous 1N NaOH
5. customdried
6. concentrationconcentrated