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HRID3934

反应详情

EQUATION

反应方程式

HRID 3934 的结构方程式

REACTANTS

反应物

2
结构：O=S(Cl)Cl
HCID24386

Thionyl chloride

Cl2OS

结构：CCCCCCCCc1ccc(-c2ccc(C(=O)O)cc2)nc1
HCID14070040

未命名化合物

PRODUCTS

生成物

1
结构：CCCCCCCCc1ccc(-c2ccc(C(=O)Cl)cc2)nc1.Cl
HCID20153528

未命名化合物

收率 96.7%

PROCEDURE

实验过程

30 g (0.102 mol) of the resulting p-(5-octylpyridyl)benzoic acid was added to 24.3 g (0.204 mol) of thionyl chloride and reflux was maintained for 5 hours. The surplus thionyl chloride was removed by distillation and the product was recrystallized from hexane to obtain 34.5 g (0.0986 mol) of p-(5-octylpyridyl)benzoylchloride hydrochloride.

WORKUP

后处理

  1. temperaturereflux
  2. temperaturewas maintained for 5 hours
  3. customThe surplus thionyl chloride was removed by distillation
  4. customthe product was recrystallized from hexane