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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 393480Generated: October 29, 2026

2,6-Dimethyl-4-(trifluoromethyl)nicotinic acid → N-[[1-[4-(methylsulfonyl)butyl]cyclopentyl]carbonyl]-L-phenylalanine

https://huagongshe.com/reaction/393480

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,6-Dimethyl-4-(trifluoromethyl)nicotinic acidHCID 22660124—
Reactant4-amino-N-[[1-[4-(methylsulfonyl)butyl]cyclopentyl]carbonyl]-L-phenylalanine methyl esterHCID 54214310—
ProductN-[[1-[4-(methylsulfonyl)butyl]cyclopentyl]carbonyl]-L-phenylalanineHCID 53916789—

Reaction Steps

4-[(2,6-Dimethyl-4-trifluoromethyl-3-pyridinyl)carbonyl]amino]-N-[[1-[4-(methylsulfonyl)butyl]cyclopentyl]carbonyl]-L-phenylalanine was prepared from 4-amino-N-[[1-[4-(methylsulfonyl)butyl]cyclopentyl]carbonyl]-L-phenylalanine methyl ester and 2,6-dimethyl-4-trifluoromethyl-3-pyridine carboxylic acid using the general procedure described in example 364.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06806365B2
Source datasetuspto-grants-2004_10
ORD IDord-be6cfc824735441bbe88a58129df44fb
Source noteuspto-grants-2004_10