HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-[4-(4-furan-2-yl-phenyl)piperazine-1-sulfonylmethyl]-N-hydroxy-3-methylbutyramide → 4-[4-(4-Bromophenyl)piperazine-1-sulfonylmethyl]-tetrahydropyran-4-carboxylic acid hydroxyamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-[4-(4-furan-2-yl-phenyl)piperazine-1-sulfonylmethyl]-N-hydroxy-3-methylbutyramide | HCID 9931969 | — |
| Reactant | 4-[4-(4-Bromophenyl)piperazine-1-sulfonylmethyl]tetrahydropyran-4-carboxylic acid | HCID 22646679 | — |
| Product | 4-[4-(4-Bromophenyl)piperazine-1-sulfonylmethyl]-tetrahydropyran-4-carboxylic acid hydroxyamide | HCID 86584769 | 87% |
Reaction Steps
Prepared according to the method for the preparation of 2-[4-(4-furan-2-yl-phenyl)piperazine-1-sulfonylmethyl]-N-hydroxy-3-methylbutyramide, from 4-[4-(4-bromophenyl)piperazine-1-sulfonylmethyl]tetrahydropyran-4-carboxylic acid (4.54 g), to yield the title compound as a white solid (4.07 g, 87%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06809100B2 |
| Source dataset | uspto-grants-2004_10 |
| ORD ID | ord-cd05d399e5d94fdeb3a9cffb1a9fb470 |
| Source note | uspto-grants-2004_10 |