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HRID393731

反应详情

EQUATION

反应方程式

HRID 393731 的结构方程式

REACTANTS

反应物

3
结构：OB(O)c1ccc(C(F)(F)F)cc1
HCID2734389

4-(Trifluoromethyl)phenylboronic acid

C7H6BF3O2

结构：CC(C)(C)OC(=O)N1CCN(c2ncc(Br)cn2)CC1
HCID21914476

tert-Butyl 4-(5-bromopyrimidin-2-yl)piperazine-1-carboxylate

C13H19BrN4O2

结构：CC(C)(C)OC(=O)N1CCN(c2ncc(-c3ccc(F)cc3)cn2)CC1
HCID69850026

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)N1CCN(c2ncc(-c3ccc(C(F)(F)F)cc3)cn2)CC1
HCID69894809

未命名化合物

收率 95%

PROCEDURE

实验过程

Prepared according to the method for the preparation of 4-[5-(4-fluorophenyl)pyrimidin-2-yl]piperazine-1-carboxylic acid tert-butyl ester, from 4-(5-bromopyrimidin-2-yl)piperazine-1-carboxylic acid tert-butyl ester (0.346 g) and 4-(trifluoromethyl)benzeneboronic acid (0.211 g), to yield the title compound as a grey solid (0.392 g, 95%).

WORKUP

后处理

  1. customPrepared