Trifluoroacetic acid → HCID 10013494, compound

HRID 393815Notes

Reaction equation

HRID 393815 reaction equation
[C:1]([C:3]1[CH:4]=[C:5]([N:9]2[CH2:13][CH2:12][C@H:11]3[CH2:14][N:15](C(OC(C)(C)C)=O)[CH2:16][C@@H:10]23)[CH:6]=[N:7][CH:8]=1)#[N:2].FC(F)(F)C(O)=O>>[N:9]1([C:5]2[CH:6]=[N:7][CH:8]=[C:3]([CH:4]=2)[C:1]#[N:2])[CH2:13][CH2:12][C@H:11]2[CH2:14][NH:15][CH2:16][C@@H:10]12

Participants

3

Reactant 2

HCID 6422Trifluoroacetic acidHCID 66758261HCID 66758261, compound

Product 1

HCID 10013494HCID 10013494, compoundYield 100%

Procedure

The product of Example 83A (1.35 g, 4.29 mmol) and trifluoroacetic acid were processed according to the procedure described in Example 64C to provide the crude title compound (>100%) which was carried directly to the next step without further purification.

Sources & evidence

ORD record
ord-2325a503c64349ca906b4b35b4a01a23
Source dataset
uspto-grants-2004_10
Patent number
US06809105B2

Reaction notes

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