Trifluoroacetic acid → HCID 9855936, compound

HRID 393821Notes

Reaction equation

HRID 393821 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([N:9]2[C@H:16]3[C@H:11]([CH2:12][CH2:13][N:14](C(OC(C)(C)C)=O)[CH2:15]3)[CH2:10]2)[CH:6]=[N:7][CH:8]=1.FC(F)(F)C(O)=O>>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([N:9]2[C@H:16]3[C@H:11]([CH2:12][CH2:13][NH:14][CH2:15]3)[CH2:10]2)[CH:6]=[N:7][CH:8]=1

Participants

3

Reactant 2

HCID 6422Trifluoroacetic acidHCID 66757213HCID 66757213, compound

Product 1

HCID 9855936HCID 9855936, compoundYield 91.2%

Procedure

The product of Example 88A (0.540 g, 1.70 mmol) and trifluoroacetic acid were processed according to the procedure described in Example 64C to provide the title compound (0.340 g, 1.55 mmol, 91% yield).

Sources & evidence

ORD record
ord-a267262e21d240a08a3348418a17cb85
Source dataset
uspto-grants-2004_10
Patent number
US06809105B2

Reaction notes

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