HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,5-bis-(1,1-dimethylethyl)-4-hydroxy-N-[(4-nitrophenyl)methyl]-benzamide → 3,4,5-trihydroxy-N-[2-(4-aminophenyl)ethyl]-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,5-bis-(1,1-dimethylethyl)-4-hydroxy-N-[(4-nitrophenyl)methyl]-benzamide | HCID 21918554 | — |
| Reactant | 3,4,5-trihydroxy-N-[2-(4-nitrophenyl)ethyl]-benzamide | HCID 21918749 | — |
| Product | 3,4,5-trihydroxy-N-[2-(4-aminophenyl)ethyl]-benzamide | HCID 21918737 | 89% |
Reaction Steps
The experimental protocol used is the same as that described for intermediate 2.2, with 3,4,5-trihydroxy-N-[2-(4-nitrophenyl)ethyl]-benzamide replacing the 3,5-bis-(1,1-dimethylethyl)-4-hydroxy-N-[(4-nitrophenyl)methyl]-benzamide. A beige powder is obtained with a yield of 89%. Melting point: 167-169° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06809088B2 |
| Source dataset | uspto-grants-2004_10 |
| ORD ID | ord-921f0481360e47c6a744318088a6046c |
| Source note | uspto-grants-2004_10 |