Sodium Iodide → HCID 54319511, compound

HRID 393881Notes

Reaction equation

HRID 393881 reaction equation
[C:1]([NH:4][C:5]1[CH:10]=[CH:9][C:8]([CH:11]=[CH:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17]S(C)(=O)=O)=[CH:7][CH:6]=1)(=[O:3])[CH3:2].[Na+].[I-:23]>CC(C)=O>[C:1]([NH:4][C:5]1[CH:10]=[CH:9][C:8]([CH:11]=[CH:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][I:23])=[CH:7][CH:6]=1)(=[O:3])[CH3:2]

Participants

4

Reactant 2

HCID 5238Sodium IodideHCID 53780631HCID 53780631, compound

Product 1

HCID 54319511HCID 54319511, compoundYield 117.7%

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

To a solution of 2.641 g (8.11 mmol) of N-acetyl-4-(7-methanesulfonyl-1-heptenyl)-aniline in 60 mL of acetone was added 1.832 g (12.2 mmol) of NaI. The reaction mixture was refluxed for 19 hr. Then, filtration and evaporation of solvent gave 3.410 g (quant) of iodide 34, which was used as is in the next reaction.

Workup

  1. temperatureThe reaction mixture was refluxed for 19 hr
  2. filtrationThen, filtration and evaporation of solvent

Sources & evidence

ORD record
ord-630aa53074e74f5e8b9389e203c307de
Source dataset
uspto-grants-2004_10
Patent number
US06809176B2

Reaction notes

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