Dichloromethane → HCID 15505948, compound

HRID 393997Notes

Reaction equation

[CH3:1][O:2][C:3]1[CH:26]=[C:25]([O:27][CH3:28])[CH:24]=[CH:23][C:4]=1[C:5]([C:7]1[C:20]2[C:21]3=[C:22]4[C:17](=[CH:18][CH:19]=2)[CH:16]=[CH:15][CH:14]=[C:13]4[CH:12]=[CH:11][C:10]3=[CH:9][CH:8]=1)=[O:6].Cl[C:30]1[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=1.C(Cl)Cl.C(Cl)Cl.[CH3:42][CH2:43]CCCC>>[CH3:1][O:2][C:3]1[CH:26]=[C:25]([O:27][CH3:28])[CH:24]=[CH:23][C:4]=1[C:5]([C:7]1[C:20]2[C:21]3[C:10]4[C:9](=[CH:42][CH:43]=[C:31]5[C:11]=4[C:12]4[C:34](=[CH:35][CH:30]=[C:14]6[C:13]=4[C:22]=3[C:17](=[CH:18][CH:19]=2)[CH:16]=[CH:15]6)[CH:33]=[CH:32]5)[CH:8]=1)=[O:6]

Participants

Reactant 4

HCID 6344Dichloromethane

HCID 7964Chlorobenzene

HCID 15505944HCID 15505944, compound

HCID 21226440Methylenechloride Hexane

Product 1

HCID 15505948HCID 15505948, compound

Procedure

The synthesis was carried out essentially as described for 2a, but chlorobenzene was used as a solvent instead of methylene chloride. Yield after column chromatography (methylene chloride/ hexane): 48%. Found: C, 85.52; H, 4.21; C33H20O3 (NM 464.51) requires C, 85.33; H, 4.34%. Mass-spectrum, MALDI-TOF: 464.22 (100), 300.1 (30). Calculated exact mass for C33H20O3:464.14125; found 464.14189 [1.4 ppm error].

Sources & evidence

ORD record: ord-392d598f54414c4daad1f435d1438149
Source dataset: uspto-grants-2004_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06809220B2

Reaction notes

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