反应详情

5-(2-Chlorophenyl)-1-(2,6-dichlorophenyl)-7-hydroxy-2(1H)-quinolinone was prepared from 5-(2chlorophenyl)-1-(2,6-dichlorophenyl)-7-methoxy-2(1H)-quinolinone (INTERMEDIATE 8) by a procedure analogous to that described in INTERMEDIATE 3. Mass spectrum (ESI) 416.05 (M+1). 1H NMR (500 MHz, CDCl3): δ 7.49-7.56 (m, 3H); 7.31-7.41 (m, 5H); 6.63 (d, J=2.0 Hz, 1H); 6.46 (d, J=9.5 Hz, 1H); 5.97 (d, J=2.0 Hz, 1H).