HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(2-Chlorophenyl)-1-(2,6-dichlorophenyl)-7-methoxy-2(1H)-quinolinone → 5-(2-Chlorophenyl)-1-(2,6-dichlorophenyl)-7-hydroxy-2(1H)-quinolinone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(2-Chlorophenyl)-1-(2,6-dichlorophenyl)-7-methoxy-2(1H)-quinolinone | HCID 22647905 | — |
| Reactant | 1-(2,6-Dichlorophenyl)-5-(2,4-difluorophenyl)-3,4-dihydro-7-hydroxy-2(1H)-quinolinone | HCID 22648093 | — |
| Product | 5-(2-Chlorophenyl)-1-(2,6-dichlorophenyl)-7-hydroxy-2(1H)-quinolinone | HCID 22647945 | — |
Reaction Steps
5-(2-Chlorophenyl)-1-(2,6-dichlorophenyl)-7-hydroxy-2(1H)-quinolinone was prepared from 5-(2chlorophenyl)-1-(2,6-dichlorophenyl)-7-methoxy-2(1H)-quinolinone (INTERMEDIATE 8) by a procedure analogous to that described in INTERMEDIATE 3. Mass spectrum (ESI) 416.05 (M+1). 1H NMR (500 MHz, CDCl3): δ 7.49-7.56 (m, 3H); 7.31-7.41 (m, 5H); 6.63 (d, J=2.0 Hz, 1H); 6.46 (d, J=9.5 Hz, 1H); 5.97 (d, J=2.0 Hz, 1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06809199B2 |
| Source dataset | uspto-grants-2004_10 |
| ORD ID | ord-021e1ea03525409182923001ecd536fc |
| Source note | uspto-grants-2004_10 |