Morpholine → HCID 22648041, compound

Participants

Reaction Steps

The title compound was prepared from 7-(bromoacetyl)-5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-3-(4-methoxybenzyl)-3,4-dihydroquinazolin-2(1H)-one and using morpholine as an amine as described in EXAMPLE ABA1. 1H NMR (CDCl3, 500MHz): δ 7.53-7.27 (m, 8H); 6.92 (s, 1H); 5.91 (brs, 1H); 4.45 (d, J=15.5 Hz, 1H); 4.28 (d, J=15.5 Hz, 1H); 3.64 (m, 4H); 3.55 (Abq, J=3.7, 15.8 Hz, 2H); 2.44 (m, 4H). Mass spectrum (ESI): 530 (M+1).

Provenance & Evidence