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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 394151Generated: October 29, 2026

Trifluoroacetic acid → HCID 22648163, compound

https://huagongshe.com/reaction/394151

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 22647983HCID 22647983—
ProductHCID 22648163HCID 22648163—

Reaction Steps

To 25 mg of 7-[3-(tert-butoxymethyl)piperazin-1-yl]-5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-1,6-naphthyridin-2(1H)-one was added 1 mL of TFA. The mixture was stirred 2 h at rt, then concentrated. The residue was purified by preparative thin-layer chromatography, eluting with 9:1 CH2Cl2-2M NH3 in MeOH.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06809199B2
Source datasetuspto-grants-2004_10
ORD IDord-c6c7aae89fc64656ba76dc1569735d51
Source noteuspto-grants-2004_10