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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 394198Generated: October 30, 2026

3-Chloropropanesulphonyl chloride → HCID 22647935, compound

https://huagongshe.com/reaction/394198

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Chloropropanesulphonyl chlorideHCID 15410—
Reactant7-amino-5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-3-(4-methoxybenzyl)-3,4-dihydroquinazolin-2(1H)-oneHCID 22648015—
ProductHCID 22647935HCID 22647935—

Reaction Steps

The 3-chloro-N-[5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-3-(4-methoxybenzyl)-2-oxo-1,2,3,4-tetrahydroquinazolin-7-yl]propane-1-sulfonamide was prepared from 7-amino-5-(2chlorophenyl)-1-(2,6-dichlorophenyl)-3-(4-methoxybenzyl)-3,4-dihydroquinazolin-2(1H)-one (COMPOUND CCC4, STEP A) and 3-chloropropane-1-sulfonyl chloride by a procedure analogous to that described in COMPOUND CCC5, STEP A: Mass spectrum (ESI) 678.1 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06809199B2
Source datasetuspto-grants-2004_10
ORD IDord-83e04b21d0894f3e8d77a9dbdcace5e5
Source noteuspto-grants-2004_10