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HRID394379

反应详情

EQUATION

反应方程式

HRID 394379 的结构方程式

REACTANTS

反应物

2
结构：[Li+].[OH-]
HCID3939

Lithium hydroxide anhydrous

HLiO

结构：CCOC(=O)C(Cc1ccc(OC(C)(C)c2cnc(-c3ccc(C(F)(F)F)cc3)s2)cc1C)OCC
HCID68617901

未命名化合物

PRODUCTS

生成物

1
结构：CCOC(Cc1ccc(OC(C)(C)c2cnc(-c3ccc(C(F)(F)F)cc3)s2)cc1C)C(=O)O
HCID22647566

未命名化合物

PROCEDURE

实验过程

In analogy to the procedure described in example 10 d], [rac]-2-ethoxy-3-(2-methyl-4-{1-methyl-1-[2-(4-trifluoromethyl-phenyl)-thiazol-5-yl]-ethoxy}-phenyl)-propionic acid ethyl ester was treated with LiOH to obtain [rac]-2-ethoxy-3-(2-methyl-4-{1-methyl-1-[2-(4-trifluoromethyl-phenyl)-thiazol-5-yl]-ethoxy}-phenyl)-propionic acid as colorless oil.

WORKUP

后处理

  1. customdescribed in example 10 d