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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 394396Generated: October 29, 2026

Sodium Hydroxide → [Rac]-2-{2-methyl-4-[4-methyl-2-(4-trifluoromethyl-phenyl)-thiazol-5-ylmethoxy]-benzyl}-heptanoic acid

https://huagongshe.com/reaction/394396

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantHCID 68617948HCID 68617948—
Product[Rac]-2-{2-methyl-4-[4-methyl-2-(4-trifluoromethyl-phenyl)-thiazol-5-ylmethoxy]-benzyl}-heptanoic acidHCID 22647429—

Reaction Steps

In analogy to the procedure described in example 10 d], [rac]-2-{2-methyl-4-[4-methyl-2-(4-trifluoromethyl-phenyl)-thiazol-5-ylmethoxy]-benzyl}-heptanoic acid methyl ester was treated with 3 N NaOH to obtain [rac]-2-{2-methyl-4-[4-methyl-2-(4-trifluoromethyl-phenyl)-thiazol-5-ylmethoxy]-benzyl}-heptanoic acid as yellow crystals.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06809110B2
Source datasetuspto-grants-2004_10
ORD IDord-fc4198e3faef417e867b579447fc4e24
Source noteuspto-grants-2004_10