反应详情

In analogy to the procedure described in example 10 d], 2-(4-{cyclopropyl-[4-methyl-2-(4-trifluoromethyl-phenyl)-thiazol-5-yl]-methoxy}-2-methyl-benzyl)-butyric acid ethyl ester (mixture of two diastereomeric racemates) was treated with LiOH to obtain 2-(4-{cyclopropyl-[4-methyl-2-(4-trifluoromethyl-phenyl)-thiazol-5-yl]-methoxy}-2-methyl-benzyl)-butyric acid as a mixture of two diastereomeric racemates as colorless liquid.

1. customdescribed in example 10 d