HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Benzyl-4-(N-Boc-amino)piperidine → 4-(N-Boc-amino)piperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Benzyl-4-(N-Boc-amino)piperidine | HCID 4438618 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-(N-Boc-amino)piperidine | HCID 723833 | 91.7% |
Reaction Steps
Compound 79 (4.55 g, 15.7 mmol), 10% palladium on carbon (400 mg), and ethanol (100 mL) were combined and hydrogenated in a Parr jar at 63psi for 3d. The mixture was filtrated through celite, followed by removal of the solvent in vacuo to afford 2.87 g (14.4 mmol, 91.4%) of Compound 80.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06602872B1 |
| Source dataset | uspto-grants-2003_08 |
| ORD ID | ord-86a809d4425a40f9a9c7b2ab0717eaa7 |
| Source note | uspto-grants-2003_08 |