HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Chlorobenzo[b]thiophene-2-sulfonyl chloride → HCID 54277563, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Chlorobenzo[b]thiophene-2-sulfonyl chloride | HCID 15158641 | — |
| Reactant | HCID 18176418 | HCID 18176418 | — |
| Product | HCID 54277563 | HCID 54277563 | — |
Reaction Steps
The title compound is prepared as described in EXAMPLE 1, Part K using 6-chloro-benzo[b]thiophene-2-sulfonyl chloride and 3-amino-1-(1-benzenesulfonyl-4-chloro-1H-pyrrolo[3,2-c]pyridin-2-ylmethyl)-pyrrolidin-2-one hydrochloride as the starting material. The crude product is purified by column chromatography eluting with a gradient of 1% MeOH/CH2Cl2 to 3% MeOH/CH2Cl2 to give the product as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06602864B1 |
| Source dataset | uspto-grants-2003_08 |
| ORD ID | ord-7613a152903e458a80142c8368f21607 |
| Source note | uspto-grants-2003_08 |