反应详情

The unsaturated compound obtained in Step A (Z+E mixture), solubilised in ethanol (20 ml), is introduced into the reactor of a Parr apparatus. 10% (by weight) palladium-on-carbon is then added. The double bond is hydrogenated at a pressure of 45 psi for 12 hours. The catalyst is removed by filtration; the solvent is then evaporated. The residual oil is purified on a silica column eluted by a mixture of AcOEt/PE 3/7. Colourless oil.

1. customThe catalyst is removed by filtration
2. customthe solvent is then evaporated
3. customThe residual oil is purified on a silica column
4. washeluted by a mixture of AcOEt/PE 3/7