Propyl isocyanate → HCID 10333771, compound

Participants

Reaction Steps

The amine obtained in Step C of Example 24 is dissolved in 16 ml of anhydrous toluene; 0.78 g (9.17 mmol) of n-propyl isocyanate is then added to the medium. After 4 hours of stirring under an inert atmosphere and at ambient temperature, the excess of isocyanate is neutralised with a few drops of water. The solvent is then evaporated in vacuo. The residue obtained is purified on a silica column (eluant: MeOH/CH2Cl2: 10/90) to yield the title urea in the form of a white solid.

Provenance & Evidence