Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 394859Generated: October 25, 2026

4,4,4-Trifluoro-1-[4-(2-furyl)phenyl]butane-1,3-dione → 5-[5-[3-Chloro-4-(1,3-oxazol-2-yl)phenyl]-3-(trifluoromethyl)-1H-pyrazol-1-yl]-2-pyridinesulfonamide

https://huagongshe.com/reaction/394859

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4,4,4-Trifluoro-1-[4-(2-furyl)phenyl]butane-1,3-dioneHCID 12114160—
Reactant5-Hydrazino-2-pyridinesulfonamide hydrochlorideHCID 22313829—
Reactant1-[3-Chloro-4-(1,3-oxazol-2-yl)phenyl]-4,4,4-trifluoro-1,3-butanedioneHCID 22313839—
Product5-[5-[3-Chloro-4-(1,3-oxazol-2-yl)phenyl]-3-(trifluoromethyl)-1H-pyrazol-1-yl]-2-pyridinesulfonamideHCID 10227064—

Reaction Steps

The subtitle compound was prepared according to the procedure of Example 1 (Step 2) using 1-[3-chloro-4-(1,3-oxazol-2-yl)phenyl]-4,4,4-trifluoro-1,3-butanedione, instead of 4,4,4-trifluoro-1-[4-(2-furyl)phenyl]butane-1,3-dione and 5-hydrazino-2-pyridinesulfonamide hydrochloride instead of 2-hydrazino-5-sulfamoylpyridine dihydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06603008B1
Source datasetuspto-grants-2003_08
ORD IDord-0b64be91799844b496292557ec8ff252
Source noteuspto-grants-2003_08