1-Chloro-4-iodobenzene → 6-(4-Chlorophenyl)hex-5-yn-1-ol

HRID 395377Notes

Reaction equation

HRID 395377 reaction equation
[CH2:1]([OH:7])[CH2:2][CH2:3][CH2:4][C:5]#[CH:6].[Cl:8][C:9]1[CH:14]=[CH:13][C:12](I)=[CH:11][CH:10]=1>>[Cl:8][C:9]1[CH:14]=[CH:13][C:12]([C:6]#[C:5][CH2:4][CH2:3][CH2:2][CH2:1][OH:7])=[CH:11][CH:10]=1

Participants

3

Reactant 2

HCID 125101-Chloro-4-iodobenzeneHCID 702345-Hexyn-1-ol

Product 1

HCID 226780576-(4-Chlorophenyl)hex-5-yn-1-ol

Procedure

In a manner described in Example 18 above, 5-hexyn-1-ol was reacted with 1-chloro-4-iodobenzene to give the title compound, MS m/Z exact mass 209.724 (M+H)(calcd. For C12H13OCl 209.70).

Sources & evidence

ORD record
ord-34f4d8a22dc34d2bb56a4ced45f42b33
Source dataset
uspto-grants-2003_08
Patent number
US06605628B1

Reaction notes

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