Benzoyl chloride → HCID 22668900, compound

HRID 395409Notes

Reaction equation

HRID 395409 reaction equation
[F:1][CH:2]([F:23])[C:3]1[C:8]([C:9]([O:11][CH3:12])=[O:10])=[C:7]([CH2:13][CH:14]2[CH2:16][CH2:15]2)[C:6]([CH2:17][OH:18])=[C:5]([C:19]([F:22])([F:21])[F:20])[N:4]=1.[C:24](Cl)(=[O:31])[C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1>C(N(CC)CC)C>[C:24]([O:18][CH2:17][C:6]1[C:7]([CH2:13][CH:14]2[CH2:15][CH2:16]2)=[C:8]([C:9]([O:11][CH3:12])=[O:10])[C:3]([CH:2]([F:1])[F:23])=[N:4][C:5]=1[C:19]([F:22])([F:20])[F:21])(=[O:31])[C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1

Participants

4

Reactant 2

HCID 7412Benzoyl chlorideHCID 22668839HCID 22668839, compound

Product 1

HCID 22668900HCID 22668900, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

Reaction of methyl 2-(difluoromethyl)-5-(hydroxymethyl)-4-(cyclopropylmethyl)-6-(trifluoromethyl)-3-pyridine-carboxylate (U.S. Pat. No. 5,169,432 example A compound A4) with Benzoyl chloride and triethylamine according to the procedure in example 99 of U.S. Pat. No. 5,169,432 gave the product.

Workup

  1. custom5,169,432 gave the product

Sources & evidence

ORD record
ord-da74760a369a4c2889e99de86521d23e
Source dataset
uspto-grants-2003_08
Patent number
US06605624B1

Reaction notes

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