HRID395510

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：COc1ccc(NC2CCN(C(=O)OC(C)(C)C)CC2)cc1

HCID2776119

tert-Butyl 4-(4-methoxyanilino)piperidine-1-carboxylate

C17H26N2O3

HCID12019237

4-chloromethyl-2-(3,4,5-trimethoxyphenyl) pyridine

C15H16ClNO3

PRODUCTS

生成物

结构：COc1ccc(N(Cc2ccnc(-c3cc(OC)c(OC)c(OC)c3)c2)C2CCN(C(=O)OC(C)(C)C)CC2)cc1

HCID22557942

未命名化合物

PROCEDURE

实验过程

4-(p-Anisidino)-1-(tert-butoxycarbonyl)piperidine (2.21 g) and 4-chloromethyl-2-(3,4,5-trimethoxyphenyl)pyridine (2.12 g) were condensed in the same manner as described in Example 9 to give the title compound.

WORKUP

后处理

customcondensed in the same manner

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-191f5ecb5c1743bc9c2789b52cdd4a5a
来源数据集: uspto-grants-2003_08
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06605620B1
来源说明: uspto-grants-2003_08

反应 SMILES

[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([NH:9][CH:10]2[CH2:15][CH2:14][N:13]([C:16]([O:18][C:19]([CH3:22])([CH3:21])[CH3:20])=[O:17])[CH2:12][CH2:11]2)=[CH:5][CH:4]=1.Cl[CH2:24][C:25]1[CH:30]=[CH:29][N:28]=[C:27]([C:31]2[CH:36]=[C:35]([O:37][CH3:38])[C:34]([O:39][CH3:40])=[C:33]([O:41][CH3:42])[CH:32]=2)[CH:26]=1>>[C:19]([O:18][C:16]([N:13]1[CH2:14][CH2:15][CH:10]([N:9]([C:6]2[CH:5]=[CH:4][C:3]([O:2][CH3:1])=[CH:8][CH:7]=2)[CH2:24][C:25]2[CH:30]=[CH:29][N:28]=[C:27]([C:31]3[CH:36]=[C:35]([O:37][CH3:38])[C:34]([O:39][CH3:40])=[C:33]([O:41][CH3:42])[CH:32]=3)[CH:26]=2)[CH2:11][CH2:12]1)=[O:17])([CH3:22])([CH3:21])[CH3:20]