HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-butyl 4-(4-methoxyanilino)tetrahydro-1(2H)-pyridinecarboxylate → 1-(tert-butoxycarbonyl)-4-[N-(4-methoxyphenyl)-N-[[2-(3,4,5-trimethoxyphenyl) pyridin-4-yl]methyl]amino]piperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-butyl 4-(4-methoxyanilino)tetrahydro-1(2H)-pyridinecarboxylate | HCID 2776119 | — |
| Reactant | 4-Chloromethyl-2-(3,4,5-trimethoxyphenyl) pyridine | HCID 12019237 | — |
| Product | 1-(tert-butoxycarbonyl)-4-[N-(4-methoxyphenyl)-N-[[2-(3,4,5-trimethoxyphenyl) pyridin-4-yl]methyl]amino]piperidine | HCID 22557942 | — |
Reaction Steps
4-(p-Anisidino)-1-(tert-butoxycarbonyl)piperidine (2.21 g) and 4-chloromethyl-2-(3,4,5-trimethoxyphenyl)pyridine (2.12 g) were condensed in the same manner as described in Example 9 to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06605620B1 |
| Source dataset | uspto-grants-2003_08 |
| ORD ID | ord-191f5ecb5c1743bc9c2789b52cdd4a5a |
| Source note | uspto-grants-2003_08 |