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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 395530Generated: October 29, 2026

4-(Methylthio)aniline → 1-(Tert-butoxycarbonyl)-4-[[4-(methylthio)phenyl]amino]piperidine

https://huagongshe.com/reaction/395530

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Methylthio)anilineHCID 66038—
Reactanttert-Butyl 4-oxopiperidine-1-carboxylateHCID 735900—
Product1-(Tert-butoxycarbonyl)-4-[[4-(methylthio)phenyl]amino]piperidineHCID 22558035—

Reaction Steps

1-(tert-Butoxycarbonyl)-4-piperidone (5.00 g) and 4-(methylthio)aniline (3.33 g) was treated in the same manner as described in Preparation Example 37 to give white powder of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06605620B1
Source datasetuspto-grants-2003_08
ORD IDord-2f1fe48e8a7e479dbfa1b3f51852b391
Source noteuspto-grants-2003_08