Thionyl Chloride → HCID 18175096, compound

HRID 395583Notes

Reaction equation

HRID 395583 reaction equation
[C:1]1([CH2:7][C:8]([NH:10][CH2:11][CH2:12][CH:13]2[C:22]3[C:17](=[CH:18][CH:19]=[C:20]([C:23]([NH:25][CH2:26][C:27]([OH:29])=O)=[O:24])[CH:21]=3)[O:16][CH2:15][CH2:14]2)=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.S(Cl)([Cl:32])=O>>[C:1]1([CH2:7][C:8]([NH:10][CH2:11][CH2:12][CH:13]2[C:22]3[C:17](=[CH:18][CH:19]=[C:20]([C:23]([NH:25][CH2:26][C:27]([Cl:32])=[O:29])=[O:24])[CH:21]=3)[O:16][CH2:15][CH2:14]2)=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 18175064HCID 18175064, compound

Product 1

HCID 18175096HCID 18175096, compound

Conditions

Temperature
60 °C

Procedure

The product obtained in Step A (3 mmol), dissolved in thionyl chloride, is stirred at 60° C. under a current of nitrogen for one hour. The thionyl chloride is evaporated off under reduced pressure and the residue is dried with the aid of a vane pump to yield the title product.

Workup

  1. customThe thionyl chloride is evaporated off under reduced pressure
  2. customthe residue is dried with the aid of a vane pump

Sources & evidence

ORD record
ord-e85f8cd54ef74a9f81c35d4c7f125d74
Source dataset
uspto-grants-2003_08
Patent number
US06605632B1

Reaction notes

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